Tianeptine sodium CAS: 30123-17-2 5-dioxide Stablon S-Dioxide Sodium Salt

AMFANI

Tianeptine sodium gishiri ne na tricyclic antidepressant, da kuma antidepressant tsarin ya bambanta da na gargajiya tricyclic antidepressants.Zai iya ƙara haɓakar 5-HT a cikin sararin samaniya, kuma yana iya samun tasirin inganta tafiyar da ƙwayoyin 5-HT.Babu alaƙa ga choline ko masu karɓar adrenaline.Tasirin antidepressant yayi kama da tricyclic, amma haƙuri ya fi tricyclic kyau.A cikin gwaje-gwajen dabba, yana iya haɓaka ayyukan kwatsam na ƙwayoyin pyramidal a cikin hippocampus kuma yana hanzarta dawo da su bayan hana aikin.Littafin sinadarai ya haɓaka sake dawowa na serotonin ta ƙwayoyin jijiya a cikin ƙwayar ƙwayar cuta da hippocampus.Ciwon sodium tineptine a cikin tsarin narkewa yana da sauri kuma cikakke.Rarraba cikin sauri, PPB har zuwa 94%.An daidaita shi gaba daya a cikin hanta ta hanyar β-oxidation da N-demethylation, kuma izinin tashar T1 / 2 ya takaice a 2.5h.Kadan daga cikin magungunan (8%) an fitar da shi daga koda, yawanci metabolites daga fitsari.Marasa lafiya tare da rashin wadatar koda sun share T1/2 don tsawan awa 1.