China Hot Sale CAS 7361-61-7 Xylazine cannabinoids farin foda

Bayani

Xylazine agonist ne na masu karɓa na α2-adrenergic (Ki = 194 nM).Yana da analog na clonidine, agonist mai karɓa na α2-adrenergic da ake amfani dashi don rage hawan jini.Ana amfani da Xylazine don kwantar da hankali, maganin sa barci, da analgesia a cikin dabbobi masu shayarwa waɗanda ba na mutum ba.Hakanan ana samun wannan samfurin azaman ma'aunin tunani na nazari.
Mafarin Xylazine, Bayer

Amfani

Antinociceptive; Alpha-2 adrenergic agonist
Amfani

Xylazine aji ne na α2 na adrenergic agonist mai karɓa.Xylazine shine analoque na clonidine wanda ke aiki akan presynaptic da masu karɓa na postsynaptic azaman 2-adrenergic agonist.
Tsarin Masana'antu

2,6-Dimethylphenyl isothiocyanate, 31.0 g (0.2 mole), wanda aka shirya daga 2,6-dimethylaniline tare da thiophosgene, an ƙara dropwise a lokacin 15 min zuwa wani dakatarwa mai kyau na 15.0 g (0.2 mole) na 3-aminopropanol-1 in 100 ml na ether.Ether ya fara tafasa.An ci gaba da motsawa a ƙarƙashin reflux na minti 30, kuma an kashe ether.An bi da ragowar tare da 100 ml na hydrochloric acid mai tattarawa kuma an dafa shi a ƙarƙashin reflux na minti 30.Bayan an sanyaya, an shafe shi da ruwa, an tace shi ba tare da datti ba, kuma tushen yana haɓaka ta hanyar ƙara yawan maganin sodium hydroxide.Lokacin da aka sake yin amfani da shi daga benzene-ligroin, sakamakon da aka samu 2- (2,6-dimethyl-phenylamino) -4H-5,6-dihydro-1,3-thiazine, ma'anar narkewa 140-142 ° C (ba da 90% na ka'idar ).
Ayyukan warkewa

Analgesic, maganin sa barci

Babban Bayani

Xylazine yana narkewa a cikin methanol (50 mg / ml), yana ba da bayani mai haske, mara launi.Hakanan yana narkewa a cikin HCl acid kuma a cikin chloroform.Xylazine a zahiri baya narkewa a cikin ruwa kuma a cikin maganin alkali.
Ayyukan Biochem/physiol

Xylazine lokacin da aka yi amfani da shi tare da ketamine ana ɗaukarsa a matsayin mai ƙarfi da aminci a cikin dabbar gwaji.An san shi yana haɓaka sakin hanta na glucose, wanda ke ƙaruwa zuwa hyperglycemia.
Hanyar aiki

Ana sayar da Xylazine azaman gishiri na hydrochloride kamar Rompun (100 mg/mL) da Anased (20 mg/mL) maganin allura don gudanarwar cikin jini ga dawakai da karnuka, bi da bi.Ayyukan xylazine na iya canzawa ta hanyar gudanar da yohimbine, wani indolalkylamine alkaloid, wanda ke toshe waɗancan α2-adrenoreceptors waɗanda xylazine ke motsa su.
Bayanan Tsaro

Guba ta hanyar sha, subcutaneous, da hanyoyin cikin jijiya.Tasirin tsarin ɗan adam: canji a cikin ayyukan motsa jiki, faɗuwar cutar hawan jini, miosis, thickening pleural, raguwar bugun jini, rashin bacci.Lokacin da zafi ya lalace yana fitar da hayaki mai guba na NOx da SOx